Capable of regrowing or reattaching his head after it is destroyed or removed by items such as The Intruder or Decap Attack), Statistics Amplification (Many if not most of Isaac's items permanently increase his statistics. Berserk! allows Isaac to survive wounds that would normally be lethal, although he will die once the berserk effect runs out), Resurrection (Can come back from the dead with various items), Regeneration (Mid.
If Isaac picks up Isaac's Heart, Isaac will become invincible, but reliant on the heart's survival to live. Danmaku, Martial Arts (With Suplex!), Immortality (Varies among Type 2, 3, 4, 7 and 8.
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